https://advanced.onlinelibrary.wiley.com/toc/21922659/2025/14/17

Journal cover / Advanced Healthcare Materials: Volume 14, Issue 17
July 4, 2025

Abstract

Parkinson’s Disease

Wireless graphene-based cortical surface implant restores motor function in Parkinsonian rats by recording pathogenic beta–gamma oscillations and delivering on-demand high-frequency stimulation that rebalances delta rhythms, strengthens mGluR5- and D5R-mediated synaptic plasticity, and upregulates glutamatergic genes. The flexible, biocompatible, minimally invasive system demonstrates integrated real-time diagnosis and therapy for neurodegenerative disorders across multiple freely moving animals. More details can be found in article 2405179 by Sungchil Yang, Sung Q Lee, Sunggu Yang, and co-workers.