Journal cover / Angewandte Chemie International Edition: Volume 64, Issue 30 July 21, 2025

https://onlinelibrary.wiley.com/toc/15213773/2025/64/30

Abstract

A hybrid metal–enzyme electrode integrating bovine carbonic anhydrase (bCA) with a metallic catalyst facilitates enhanced CO2 electroreduction. The bCA dynamically catalyzes the reversible conversion between CO2 and bicarbonate, enabling local CO2 regeneration at the catalyst surface. This enzyme-mediated CO2 supply significantly boosts CO2RR current density beyond mass transfer limits, even under flooding conditions, as reported by Jinwoo Lee, Jungbae Kim, Ki Tae Park et al. in their Research Article (e202504380).